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Treating West Nile Virus with Excessive High quality St. John’s Wort

Treating West Nile Virus with Excessive High quality St. John’s Wort

West Nile Virus, though new to the U.S., is
well-documented. The Facilities for Illness Management
identifies it as a flavivirus, a member of the
Togavirus household. It’s intently associated to yellow
fever and dengue fever. That is vital as a result of
the Togavirus household are encapsulated viruses,
i.e., they’re lined with a lipid (fatty)
coating.

That is thrilling, as a result of it means the virus is
accessible to therapy using prime quality St.
John’s Wort (SJW). A number of research have been accomplished
on quite a lot of encapsulated viruses, together with
herpes simplex virus sorts 1 and a pair of, parainfluenza
virus, vaccinia virus, cytomegalovirus and a number of other
retroviruses together with HIV1, 2, 3, 4, 8, 9, 10.

Non-encapsulated viruses or “bare” viruses had been
additionally studied for comparability purposes10,13.

SJW was a potent anti-viral agent throughout quite a lot of
encapsulated virus households, however confirmed no
exercise in opposition to bare viruses.

In contrast to a vaccine that’s particular to every
organism, SJW is energetic in opposition to encapsulated
viruses by quite a lot of mechanisms, together with
gentle activation, interference with DNA
transcription, impairing the meeting of intact
viral particles and the lipophilic (fat-loving)
nature of the ring buildings (the quinone and
phenolic teams)4, 6, 7, 9, 11, 12, 13, 14, 15.
These ring buildings are important to the biologic
exercise of SJW.

From these outcomes, it’s cheap to make use of excessive
high quality, pharmaceutical grade SJW in combating
West Nile Virus, since there aren’t any efficient
pharmaceutical brokers.

High quality is important for the reason that stage of hypericin
and pseudohypericin are
key. I can solely advocate the SJW product
produced by Medi-Herb, which is a pharmaceutical
home in Australia, adhering to pharmaceutical
manufacturing requirements. The product is
distributed by Normal Course of via
different well being care practitioners, together with
medical doctors of chiropractic, acupuncturists and
veterinarians. SJW is sort of unstable and the
energetic elements degrade on retailer cabinets. An
impartial evaluation of three merchandise (all of which
had been licensed to comprise 0.3% hypericin) had been
proven to be broadly variant, with one product 25%
under label claims. It’s critically vital
that the phytochemical integrity of the entire
plant be preserved for optimum efficacy.16

References:
1Andersen DO, Weber ND, Wooden SG et al. Antiviral
Res 1991; 16(2): 185-196.
2Lopez-Bazzocchi I, Hudson JB, Towers GHN.
Photochem.Photopbiol. 1991; 54(1): 95-98.
3Moraleda G, Wu TT, Jilbert AR et al. Antiviral
Res 1993; 20: 235-247.
4Tang J, Colacino JM, Larsen SH et al. Antiviral
Res 1990; 13 (6): 313-325.
5Hudson JB, Harris L, Towers GHN. Antiviral Res
1993; 20 (2):173-178.
6Lenard J, Rabson A, Vanderoef R. Proc Natl Acad
Sci USA 1993; 90 (1): 158-162.
7Degar S, Prince AM, Pascual D et al. AIDS Res Hum
Retroviruses 1992; 8 (11): 1929-1936.
8Carpenter S, Kraus GA. Photochem Photobiol 1991;
53 (2): 169-174.
9Lavie G, Valentine F, Levin B et al. Proc Natl
Acad Sci USA 1989; 86 (15): 5963-5967.
10Meruelo D, Lavie G, Lavie D et al. Proc Natl
Acad Sci USA 1988; 85 (14): 5230-5234.
11Kraus GA, Pratt D, Tossberg J et al. Biochem
Biophys Res Commun 1990; 172 (1): 149-153.
12Takahashi I, Nakanishi S, Kobayashi E et al.
Biochem Biophys Res Commun 1989; 165 (3):
1207-1212.
13De Witte P, Agostinis P, Van Lint J et al.
Biochem Pharmacol 1993; 46 (11): 1929-1936.
14Panossian AG, Gabrielian E, Manvelian V et al.
Phytomed 1996; 3 (1): 19-28.
15Lavie G, Mazur Y, Lavie D et al. Transfusion
1995; 35 (5): 392-400.
16Constantine GH, Karchesy J. Variations in
Hypericin concentrations in Hypericum perforatum
L. and industrial merchandise. Pharmaceutical
Biology 1998; 36 (5): 365-367.

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Treating West Nile Virus with Excessive High quality St. John’s Wort

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